Involvement and detachment in intellectual disability studies
نویسندگان
چکیده
منابع مشابه
Genetic Studies in Intellectual Disability and Behavioral Impairment.
Intellectual Disability (ID, also known as mental retardation) is a debilitating neurodevelopmental disorder affecting nearly 1% of the general population worldwide. Occurrence of behavioral disorders in individuals with ID is four times higher than that in the general population. An increasing number of studies seek to find a common pathway to elucidate brain structure/function and its contri...
متن کاملAneuploidy and Intellectual Disability
Aneuploidy is the presence of an abnormal number of chromosomes in cells. The gain or loss of a chromosome in germ cells is the most common cause of chromosomal aneuploidy. Trisomy 21, trisomy 18, and trisomy 13 are characterized by congenital anomalies with intellectual disability (ID) or short lives. Recently, mosaic variegated aneuploidy (the presence of a different number of chromosomes in ...
متن کاملInv21p12q22del21q22 and intellectual disability.
Chromosomal rearrangements are common in humans. Pericentric inversions are among the most frequent aberrations (1-2%). Most inversions are balanced and do not cause problems in carriers unless one of the breakpoints disrupts important functional genes, has near submicroscopic copy number variants or hosts "cryptic" complex chromosomal rearrangements. Pericentric inversions can lead to imbalanc...
متن کاملGenetic testing in intellectual disability psychiatry: Opinions and practices of UK child and intellectual disability psychiatrists
BACKGROUND An increasing number of genetic causes of intellectual disabilities (ID) are identifiable by clinical genetic testing, offering the prospect of bespoke patient management. However, little is known about the practices of psychiatrists and their views on genetic testing. METHOD We undertook an online survey of 215 psychiatrists, who were contacted via the Royal College of Psychiatris...
متن کاملInvolvement of the kinesin family members KIF4A and KIF5C in intellectual disability and synaptic function.
INTRODUCTION Kinesin superfamily (KIF) genes encode motor proteins that have fundamental roles in brain functioning, development, survival and plasticity by regulating the transport of cargo along microtubules within axons, dendrites and synapses. Mouse knockout studies support these important functions in the nervous system. The role of KIF genes in intellectual disability (ID) has so far rece...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scandinavian Journal of Disability Research
سال: 2001
ISSN: 1501-7419,1745-3011
DOI: 10.1080/15017410109510775